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BIO 4410 -- Developmental Biology
Syllabus -- Fall, 2013

Instructor: Dennis . Sullivan, MD


Course Goals - Students will:

  1. learn the basic principles of human embryology and development.
  2. develop critical thinking skills, and will learn to visualize three-dimensionally.
  3. correlate development with postnatal anatomy
  4. analyze key clinical and ethical issues in the light of fetal development.

Instructor: Dennis Sullivan, MD - HSC 229 (phone ext. 7573)
Home Phone: 937-426-0597 (before 9:00 p.m., please)

Textbook: Larsen's Human Embryology (Fourth Edition), by Gary C. Schoenwolf, et al. Churchill Livingstone, 2009.


Lab Manual: A Photographic Atlas of Developmental Biology, by Shirley Wright, Morton, 2005.

Course Resources: This Website, plus Simbryo software (CedarNet).

Course Content: Three 50-minute lectures and one two-hour lab per week.

Evaluation: Three mid-term lecture exams (multiple choice), plus a comprehensive lecture final. A copy of each midterm exam answer key will be available in my office for one week only after the exam. There will also be two lab practical exams.

Grading: The total course grade is based on 400 points:

  • 3 Lecture exams @ 60 = 180
  • 2 Lab exams @ 50 = 100
  • Final exam(comprehensive: lab + lecture) = 120

Exam Policy (Please review, elsewhere on this Web site)

Grading Policy (Please review, elsewhere on this Web site)

    Lecture Schedule and Reading Assignments:

Date

Topic

Reading Assignment (pages)

 W

08/21

Introduction, Reproductive A&P

1-13 (supplement with A&P text)

 F

08/23

Cell Cycle, Mitosis, Meiosis

15-25

Lab:

(no lab this week)

 M

08/26

Gametogenesis I

25-28

 W

08/28

(Class cancelled)  

 F

08/30

Gametogenesis II

28-39

Lab:

Fertilization, Cleavage, Implantation

39-49

 

 M

09/02

LABOR DAY (no classes)

 W

09/04

Bilaminar Disc, Clinical (Ectopic)

51-58

 F

09/06

Uteroplacental Circulation, Molar Pregnancies

58-64

Lab:

Reproductive tissues

 M

09/09

Imprinting, Gastrulation

64-72; 78-82

 W

09/11

Notochord, Somites, neural plate

83-98

 F

09/13

Embryonic Folding

103-106

Lab:

Cleavage, Morula, Blastocyst, Gastrulation  

 M

09/16

Neural Tube Formation, clinical

107-117

 W

09/18

Secondary Neurulation, Neural Crest Cells

117-129

 F

09/20

Ethics and the Embryo

Special Reading (Condic)

Lab:

Neurulation

 M

09/23

Lecture Exam #1

 

 W

09/25

Fetal Development and the Fetus as Patient

167-179

 F

09/27

Twinning, Prenatal Assessment, Treatment in Utero

179-189

Lab:

Lab Review

18-hr chick, 24-hr chick; 28-hr chick

 

reproductive histology

 M

09/30

Somite Differentiation

217-228

 W

10/02

Myotomes, Dermatomes, Bone, Limb Muscles

229-244

 F

10/04

Presidential Inauguration (no class)

 

Lab:

Lab Practical Exam #1

 M

10/07

CNS: Vesicles, Neural Tube

247-257

 W

10/09

CNS: Spinal Cord, Brain, Rhombencephalon

257-268

 F

10/11

CNS: Mesencephalon

270-272

Lab:

Lecture: CNS: Forebrain I

272-275

 M

10/14

CNS: Forebrain II

282-290

 W

10/16

CNS Review, Peripheral Nervous System

297-311

 F

10/18

(FALL BREAK)

(no classes)

Lab:

 

(no lab)

 M

10/21

Peripheral Nervous System

313-316

 W

10/23

Lecture Exam II  

 F

10/25

Respiratory System

Lab:

Organogenesis (chick)

319-326

 M

10/28

Body Cavities

329-336

 W

10/30

Heart I

337-348

 F

11/01

No Class: Instructor Out of Town

 

Lab:

(No Lab)  

 

 M

11/04

Heart II 350-354

 W

11/06

Heart III

355-366

 F

11/08

Heart IV

367-375; 378-383

 

Lab:

Short Lecture: Cardiac Defects; Lab: Organogenesis

 

 M

11/11

Vasculogenesis

385-402

 W

11/13

Aortic Arches, Arteries

402-418

 F

11/15

Veins, Circulatory Changes at Birth

419-425; 429-432

Lab:

Clinical and Anatomical Correlation (cadaver)

 M

11/18

Lecture Exam III

 

 W

11/20

GI Tract I

435-445

 F

11/22

GI Tract II

446-455

Lab:

 

(No lab)

 

 M

11/25

GI Tract III

456-476

 W

11/27

THANKSGIVING BREAK (no classes)

 F

11/29

THANKSGIVING BREAK

(no classes)

       

 M

12/02

Renal I

479-489

 W

12/04

Renal II

495-499

 F

12/06

Genital

500-519

Lab:

Lab Practical Exam #2

Lab Review: 33-hr. chick, 48-hr. chick, 72-hr. chick

 

 

 M

12/09

Genital

500-519

W

12/11

   

 F

12/13

FINAL EXAM (comprehensive, lecture & lab)

(10:30-12:30)

 

 

 

 


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