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BIO 4410 -- Developmental Biology
Syllabus -- Fall, 2014

Instructor: Dennis . Sullivan, MD


Course Goals - Students will:

  1. learn the basic principles of human embryology and development.
  2. develop critical thinking skills, and will learn to visualize three-dimensionally.
  3. correlate development with postnatal anatomy
  4. analyze key clinical and ethical issues in the light of fetal development.

Instructor: Dennis Sullivan, MD - HSC 229 (phone ext. 7573)
Home Phone: 937-426-0597 (before 9:00 p.m., please)

Textbook: Larsen's Human Embryology (Fourth Edition), by Gary C. Schoenwolf, et al. Churchill Livingstone, 2009.


Lab Manual: A Photographic Atlas of Developmental Biology, by Shirley Wright, Morton, 2005.

Course Resources: This Website, plus Simbryo software (CedarNet).

Course Content: Three 50-minute lectures and one two-hour lab per week.

Evaluation: Three mid-term lecture exams (multiple choice), plus a comprehensive lecture final. A copy of each midterm exam answer key will be available in my office for one week only after the exam. There will also be two lab practical exams.

Grading: The total course grade is based on 400 points:

  • 3 Lecture exams @ 60 = 180
  • 2 Lab exams @ 50 = 100
  • Final exam(comprehensive: lab + lecture) = 120

Exam Policy (Please review, elsewhere on this Web site)

Grading Policy (Please review, elsewhere on this Web site)

    Lecture Schedule and Reading Assignments:

Date

Topic

Reading Assignment (pages)

       

Note: Textbook Glossary Available Online:

(Glossary)

 W

08/20

Introduction, Reproductive A&P

1-13 (supplement with A&P text)

 F

08/22

Cell Cycle, Mitosis, Meiosis

15-25

Lab:

(no lab this week)

 M

08/25

Gametogenesis I

25-28

 W

08/27

Gametogenesis II

28-39

 F

08/29

Fertilization, Cleavage, Implantation

39-49

Lab:

Reproductive tissues  

 

 M

09/01

LABOR DAY (no classes)

 W

09/03

Bilaminar Disc, Clinical (Ectopic)

51-58

 F

09/05

Uteroplacental Circulation, Molar Pregnancies

58-64

Lab:

Cleavage, Morula, Blastocyst, Gastrulation

 M

09/08

Imprinting, Gastrulation

64-72; 78-82

 W

09/10

Notochord, Somites, neural plate

83-98

 F

09/12

Embryonic Folding

103-106

Lab:

 

 

 M

09/15

Neural Tube Formation, clinical

107-117

 W

09/17

Secondary Neurulation, Neural Crest Cells

117-129

 F

09/19

Ethics and the Embryo

Special Reading (Condic)

Lab:

Neurulation

       

 M

09/22

Lecture Exam #1

 

 W

09/24

Fetal Development and the Fetus as Patient

167-179

 F

09/26

Twinning, Prenatal Assessment, Treatment in Utero

179-189

Lab:

Lab Review

18-hr chick, 24-hr chick; 28-hr chick

 

reproductive histology

 M

09/29

Somite Differentiation

217-228

 W

10/01

Myotomes, Dermatomes, Bone, Limb Muscles

229-244

 F

10/03

CNS: Vesicles, Neural Tube

247-257

Lab:

Lab Practical Exam #1

 M

10/06

CNS: Spinal Cord, Brain, Rhombencephalon

257-268

 W

10/08

CNS: Mesencephalon

270-272

 F

10/10

CNS: Forebrain I

272-275

Lab:

 

 

 M

10/13

CNS: Forebrain II

282-290

 W

10/15

CNS Review, Peripheral Nervous System

297-311

 F

10/17

(FALL BREAK)

(no classes)

Lab:

 

(no lab)

       

 M

10/20

Peripheral Nervous System

313-316

 W

10/22

Lecture Exam II  

 F

10/24

Respiratory System

Lab:

Organogenesis (chick)

319-326

 M

10/27

Body Cavities

329-336

 W

10/29

Heart I

337-348

 F

10/31

Heart II 350-354

Lab:

Lecture: Heart III

355-366

 

 M

11/03

Heart IV

367-375; 378-383

 W

11/05

Cardiac Defects

 

 F

11/07

(No Class - Instructor out of town)

 

 

Lab:

(No lab)

 

       

 M

11/10

(No Class - Instructor out of town)

 

 W

11/12

Vasculogenesis, Aortic Arches, Arteries

385-418

 F

11/14

Veins, Circulatory Changes at Birth

419-425; 429-432

Lab:

Lab: Organogenesis

       

 M

11/17

Lecture Exam III

 

 W

11/19

GI Tract I

435-445

 F

11/21

GI Tract II

446-455

Lab:

Clinical and Anatomical Correlation (cadaver)

 

 

 M

11/24

GI Tract III

456-476

 W

11/26

THANKSGIVING BREAK (no classes)

 F

11/28

THANKSGIVING BREAK

(no classes)

       

 M

12/01

THANKSGIVING BREAK

(no classes)

 W

12/03

Renal I

479-489

 F

12/05

Renal II

495-499

Lab:

Lab Practical Exam #2

Lab Review: 33-hr. chick, 48-hr. chick, 72-hr. chick

 

 

 M

12/08

Genital

500-519

W

12/10

FINAL EXAM (comprehensive, lecture & lab content)

(10:30-12:30)

 F

12/13

   

 

 

 

 


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